Relfydess: The New Generation of Anti-Wrinkle Treatment
Posted March 18, 2026
The world of cosmetic injectables is evolving quickly, and Relfydess is one of the most exciting new developments in neuromodulator treatments.
Designed to smooth wrinkles while maintaining natural facial movement, Relfydess represents a new generation of botulinum toxin treatments that promise faster onset, longer-lasting results, and a more natural feel.
At Face Value in Christchurch, Medical Director Dr Phil Frost was selected as one of only 10 expert injectors in New Zealand to trial Relfydess before its wider release.
“I’ve had very pleasing outcomes. Over 35% of clients see results within one day, and the results often last up to six months. It feels softer and more natural compared with previous formulations.” —Dr Phil Frost, Face Value
If you’re considering anti-wrinkle injections and wondering how Relfydess compares to treatments like Botox or Dysport, this guide explains everything you need to know.
What Is Relfydess?
Relfydess is a neuromodulator treatment used to temporarily reduce the appearance of wrinkles caused by muscle movement, particularly:
- Frown lines between the eyebrows (glabellar lines)
- Crow’s feet around the eyes (lateral canthal lines)
- Forehead lines
Like other botulinum toxin treatments, it works by relaxing specific facial muscles, which allows the skin above them to smooth out.
However, Relfydess differs from traditional options because it was designed with advanced purification and formulation technology.
According to the manufacturer, it is the first and only liquid neuromodulator developed with PEARL™ Technology. This technology helps preserve the integrity of the product, which helps it remain more effective.
What Makes Relfydess Different?
While treatments like Botox, Dysport, and Xeomin have been widely used for years, Relfydess introduces several innovations.
1. Ready-to-Use Liquid Formulation
Most botulinum toxin treatments arrive as a powder that must be reconstituted with saline before injection.
Relfydess is different because it comes pre-prepared as a liquid formulation, which:
- Removes the need for reconstitution
- Helps ensure consistent dosing
- Simplifies preparation for clinicians
This formulation was designed to maintain the integrity of the active molecule from production through injection.
2. Faster Onset of Results
One of the biggest frustrations with traditional anti-wrinkle injections is waiting several days to see results.
Clinical studies have shown:
- Up to 39% of patients saw visible improvement within one day
- Median onset occurs within 2–3 days
This is significantly faster than many traditional neuromodulators.
Dr Frost’s experience in clinical practice aligns with these findings.
“Often over 35% of my clients see an onset within 24 hours.”
3. Longer-Lasting Effects
Another potential advantage is longevity.
Clinical trial data suggests that up to 75% of patients had not returned to baseline wrinkle severity after six months.
For many patients, this means:
- Fewer treatments per year
- Longer-lasting smoothing of wrinkles
Dr Frost notes that for frown lines in particular, Relfydess often lasts around six months, which may be two months longer than some older formulations.
4. Highly Purified Formula
Relfydess is manufactured to be:
- Complexing protein-free
- Free from human- or animal-derived components
- Highly purified
This advanced purification is designed to improve stability and consistency.
What Areas Can Relfydess Treat?
Relfydess is commonly used to treat dynamic wrinkles caused by repeated facial movement.
Glabellar lines (frown lines)
The vertical lines between the eyebrows, which are caused by frowning.
Crow’s feet
Fine lines around the outer corners of the eyes that appear when smiling.
Forehead lines
Horizontal lines that develop when raising the eyebrows.
Clinical studies evaluating Relfydess specifically looked at:
- Glabellar lines at maximum frown
- Lateral canthal lines when smiling
However, experienced cosmetic doctors may use it more broadly depending on patient needs.
Relfydess vs Botox: What’s the Difference?
Many patients ask how Relfydess compares to well-known treatments.
| Feature | Relfydess | Botox |
| Formulation | Ready-to-use liquid | Powder requiring mixing |
| Onset | Often within 1-3 days | Typically 3-7 days |
| Duration | Up to ~6 months | Typically 3-4 months |
| Feel | Often described as softer and natural | Varies |
While Botox remains an excellent treatment option, Relfydess offers an alternative that may provide faster and longer-lasting results for some patients.
What Does Relfydess Treatment Feel Like?
Treatment is very similar to other anti-wrinkle injections.
Most appointments take 15–20 minutes and involve a few small injections into targeted facial muscles.
You may experience:
- Mild pinching during injection
- Slight redness or swelling afterward
- Occasionally small bruises
These effects usually resolve within a day or two.
How Long Does Relfydess Last?
Results vary between individuals, but typical timelines are:
- Initial effects: 1-3 days
- Full results: around 1-2 weeks
- Duration: about 4-6 months
Because Relfydess may last longer for some patients, it may require fewer treatments per year compared with traditional neuromodulators.
Is Relfydess Safe?
Like all botulinum toxin treatments, Relfydess has been extensively studied in clinical trials.
It has demonstrated:
- A favourable safety profile
- Low rates of treatment-related adverse events
- High patient satisfaction levels
In one clinical study:
- 98% of patients said they would recommend the treatment
- 97% were satisfied with how natural their facial expressions looked
Possible side effects may include:
- Mild bruising
- Headache
- Temporary eyelid drooping
- Injection site discomfort
These effects are usually mild and temporary.
Why Choose Face Value for Relfydess in Christchurch?
When choosing injectable treatments, the experience of the practitioner matters even more than the brand of product used.
Face Value is widely respected in New Zealand’s cosmetic medicine community.
Dr Phil Frost was selected as one of only 10 clinical expert injectors in New Zealand to trial Relfydess before its broader rollout.
This recognition reflects:
- His extensive experience with neuromodulators
- His senior status within the New Zealand Society of Cosmetic Medicine
- Face Value’s strong reputation nationwide
For patients, this means access to one of the earliest and most experienced Relfydess providers in the country.
Is Relfydess Right for You?
Relfydess may be an excellent option if you want:
- Faster-acting anti-wrinkle injections
- Results that may last longer
- Natural-looking facial movement
However, the best treatment always depends on your individual anatomy and goals.
A consultation allows your practitioner to determine whether Relfydess, Botox, or another treatment will provide the best outcome.
Relfydess FAQs
How quickly does Relfydess work?
Some patients see results within 24 hours, although most people begin noticing improvement within 2–3 days. Clinical studies show that up to 39% of patients saw visible improvement by Day 1.
How long does Relfydess last?
Results typically last 4–6 months, depending on the treatment area and the individual patient.
Clinical studies found that up to 75% of patients had not returned to baseline wrinkle severity after six months, suggesting longer-lasting results for many people.
Is Relfydess better than Botox?
Relfydess is not necessarily “better,” but it offers some different advantages compared with Botox and similar neuromodulators.
Potential benefits include:
- Faster onset of results
- Longer duration for some patients
- Ready-to-use liquid formulation
- High levels of patient satisfaction
The best option depends on your individual anatomy, treatment goals, and your clinician’s recommendation.
Is Relfydess more expensive than Botox?
At present, Relfydess treatments are generally priced similarly to other anti-wrinkle injections such as Botox or Dysport.
However, if results last longer, some patients may find they need fewer treatments per year, which could make it more cost-effective over time.
Does Relfydess look natural?
Yes. One of the goals of modern neuromodulators is to smooth wrinkles while preserving natural facial expression.
Clinical studies found that 97% of patients were satisfied with how natural their face looked after treatment.
What areas can Relfydess treat?
Relfydess is most commonly used to treat dynamic wrinkles, including:
- Frown lines between the eyebrows (glabellar lines)
- Crow’s feet around the eyes
- Forehead lines
These wrinkles are caused by repeated muscle movement over time.
Who is a good candidate for Relfydess?
Relfydess may be suitable for adults who:
- Have moderate to severe dynamic wrinkles
- Want a non-surgical cosmetic treatment
- Prefer natural-looking results
- Are in good overall health
A consultation with an experienced cosmetic practitioner is necessary to determine if it is appropriate for you.
How long does a Relfydess treatment take?
Most appointments take 15–20 minutes, making it a convenient lunchtime treatment.
The procedure involves several small injections into specific facial muscles and requires little to no downtime.
Are there side effects from Relfydess?
Side effects are generally mild and temporary.
Possible effects include:
- Injection site redness or bruising
- Headache
- Temporary eyelid drooping (rare)
Your practitioner will discuss all risks and precautions during your consultation.
How often should you get Relfydess treatments?
Most patients repeat treatment two to three times per year, depending on how long their results last.
Because Relfydess may last longer for some people, treatments may be required less frequently than traditional anti-wrinkle injections.
Book a Relfydess Consultation in Christchurch
If you’re interested in trying the newest generation of anti-wrinkle treatment, Relfydess may be worth considering.
At Face Value, our experienced cosmetic practitioners will assess your skin, discuss your goals, and recommend the best treatment plan.
Book a consultation today to find out if Relfydess is right for you.